
HealthiCare’s new Bi-Est cream combines estriol and estradiol in a personalized topical prescription for menopause care, with licensed provider review, ongoing clinical support, and delivery directly to your door.
Menopause can change the way you feel in ways that are hard to ignore. Hot flashes, night sweats, disrupted sleep, mood changes, vaginal dryness, and brain fog can make everyday life feel different, especially when symptoms start showing up at the same time. Finding the right treatment can feel just as complicated, with different medications, formulations, appointments, and questions about what might actually be right for you.
HealthiCare is making menopause care a little simpler with the introduction of its new personalized Bi-Est cream. Bi-Est combines two forms of bioidentical estrogen, estriol (E3) and estradiol (E2), in one topical compounded prescription. Each treatment is reviewed and prescribed by a licensed medical provider based on your symptoms, health history, and individual needs.

Bi-Est is a compounded topical cream that combines two forms of estrogen, estriol (E3) and estradiol (E2), into one personalized prescription. Estriol is a naturally occurring form of estrogen, while estradiol is the primary form of estrogen produced by the body during the reproductive years. As estrogen levels change during perimenopause and menopause, those shifts can contribute to symptoms that affect everything from sleep and comfort to mood and everyday well-being.
The idea behind Bi-Est is simple: two forms of estrogen combined into one convenient cream. Instead of taking a pill, Bi-Est is applied topically to the skin as directed by your healthcare provider, making it an easy addition to an existing daily routine.
Bi-Est is personalized to each patient based on their symptoms, health history, and individual needs. A licensed medical provider reviews the information provided during the intake process and determines whether Bi-Est is an appropriate option and what formulation is right for you.
For women looking for a personalized approach to menopause care, Bi-Est offers a simple way to incorporate estrogen therapy into a daily routine, with the convenience of having treatment delivered directly to your door.
Menopause isn’t simply about a changing menstrual cycle. Hormonal changes during perimenopause and menopause can affect several parts of daily life, and symptoms can look different from one person to another.
For some women, hot flashes and night sweats are the biggest frustration. For others, sleep disruption, mood changes, vaginal dryness, or brain fog may be more noticeable. Sometimes several symptoms appear together, making it difficult to pinpoint why someone suddenly doesn’t feel quite like themselves.
Hormone therapy is commonly used to help address certain menopause symptoms, including hot flashes, night sweats, and vaginal symptoms. Whether hormone therapy is appropriate, and which treatment makes sense, depends on the individual and should be determined with a qualified medical provider.
That personalized piece is important. Menopause care shouldn’t start with a generic prescription and end there. It should start with an actual conversation about what’s happening and continue with medical support as treatment progresses.
One of the features that makes HealthiCare’s Bi-Est different is its topical format.
Bi-Est is applied to the skin, providing an alternative for women who don’t want a traditional oral medication or patch. The prescription is personalized by the provider, and the medication is prepared by a licensed U.S. pharmacy and shipped directly to the patient’s home if prescribed.
For some people, simplicity matters. A treatment that fits naturally into an existing routine can be easier to maintain than one that adds another complicated step to an already busy day.
The cream format also gives women another option to discuss with their provider. It isn’t necessarily the right choice for everyone, but having choices is an important part of personalized menopause care.
HealthiCare doesn’t treat menopause as a one-size-fits-all experience.
The process begins with an online medical intake that asks about symptoms, health history, and previous treatment. A licensed medical provider then reviews that information and determines whether treatment is appropriate and which prescription should be used.
That means the treatment isn’t simply selected from a menu based on age or a list of symptoms. Your provider has the opportunity to consider the bigger picture before deciding whether Bi-Est is an appropriate option.
And treatment doesn’t stop once the medication arrives.
HealthiCare provides ongoing clinical support throughout treatment, including the ability to discuss questions, check-ins, and dose adjustments with your provider when appropriate.
This is one of the most important questions to understand when considering estrogen therapy.
For women with a uterus who receive systemic estrogen, a progestogen is generally needed to help protect the uterine lining. Whether progesterone is appropriate for you is determined by your prescribing provider.
HealthiCare’s personalized Bi-Est treatment may include progesterone when the prescribing physician determines that it is appropriate. In those cases, the personalized topical treatment can include estriol, estradiol, and progesterone in one cream.
This is another reason medical oversight matters. Hormone therapy isn’t something that should be approached as a one-size-fits-all product. Your medical history and individual needs should guide the treatment decision.
Starting menopause treatment shouldn’t require rearranging your entire life.
HealthiCare’s online process is designed to make accessing care more convenient. After completing the medical intake, a licensed provider reviews the information and determines whether treatment is appropriate. If prescribed, the medication is prepared by a licensed U.S. pharmacy and shipped directly to your home. Ongoing clinical support is available throughout treatment.
There are no unnecessary pharmacy trips, no separate membership fee, and no need to sit in a waiting room just to begin the process.
The current price for HealthiCare’s personalized Bi-Est cream is $129.99 per month. That includes the personalized prescription, licensed medical provider review, medication, ongoing clinical support, and free shipping. Treatment eligibility and the actual prescription are determined by a licensed medical provider.
There isn’t one universal menopause experience, so there shouldn’t be one universal approach to menopause treatment.
For some women, symptoms are manageable with lifestyle changes and don’t require hormone therapy. For others, symptoms become disruptive enough that treatment is worth discussing with a medical provider. Some may prefer an FDA-approved hormone therapy, while others may be interested in a compounded option such as Bi-Est after discussing the benefits and considerations with their provider.
HealthiCare’s new Bi-Est cream gives eligible patients another option to consider as part of personalized menopause care.
It’s simple in concept: two forms of estrogen, one topical cream, personalized medical oversight, and ongoing support. More importantly, it gives women another way to have a conversation about treatment when menopause symptoms are interfering with the way they want to live.
Feeling different during menopause doesn’t mean you have to simply accept feeling unlike yourself. The right next step starts with understanding your options and having an honest conversation with a qualified medical provider about what may be appropriate for you.
September 15, 2026